After adding increasing doses of I3C and genistein to two prostate cancer and two breast cancer cell lines, the scientists found a rise in levels of certain proteins which repair damaged DNA. Additionally, when researchers added I3C and genistein together in low doses to the cell lines, the results were synergistic, providing greater benefit than that obtained by either compound alone.

The finding could explain, in part, the protective effect these compounds have shown against some cancers. The study is also among the first to discover a cellular explanation behind the ability of increased vegetable intake to reduce the risk of cancer.

Article Source: British Journal of Cancer (2006) 94, 407-426.

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63 studies were reviewed by researchers (studies starting 1966 to 2004) that examined the relationship between vitamin D and certain types of cancer. A protective relationship was found in the majority of studies, between sufficient vitamin D status and lower risk of cancer, especially in cancers of the ovary, breast, prostate and colon.

Diet and exposure to sunlight are they ways Vitamin D is acquired. Dietary sources can include products such as milk, yogurt, cheese and fortified orange juice. A typical serving provides approximately 100 international units (IU). Raising the overall intake to 1,000 IUs per day is suggested by researches, as well as considering a Vitamin D supplement. This could be especially important for people living in areas, where shorter days and longer nights result in less vitamin D from sunlight.

Evidence from the study suggests that improving vitamin D status through diet and supplements could reduce cancer incidence and mortality with few or no adverse effects and very low cost.

Article Source: American Journal of Public Health. Feb 2006. 96(2):252-61.

Other recently published studies show vitamin D exerts anti-cancer benefits for both men and women in regards to breast, prostate, and lung cancer. See below:

* Vitamin D intake and breast cancer risk in postmenopausal women: the Iowa Women’s Health Study. Article Source: Cancer Causes Control. Sep 2007. 18(7):775-82. Epub 2007 Jun 5.

* Protective role of 1, 25-dihydroxyvitamin D3 against oxidative stress in nonmalignant human prostate epithelial cells. Article Source: International Journal of Cancer. Jun 2008. 122(12):2699-706.

* Vitamin D receptor expression in normal, premalignant, and malignant human lung tissue. Article Source: Cancer Epidemiol Biomarkers Prev. May 2008. 17(5):1104-10.

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